Sentence examples for establishment of tolerance from inspiring English sources
A key element in the formation of pathological microenvironments is the establishment of tolerance and cooperation between the different players, enabling an acute process to become chronicized.
More recently, integrated pest management attempts to improve control with a combination of surveys to determine the size and distribution of the pest population, the establishment of tolerance limits (levels of pest activity at which to intervene), interventions, and evaluation of effectiveness based on repeated surveys.
However, as there is no described cellular or clinical role for SMILE, it is not yet known if SMILE has an active role in the establishment of tolerance, or if this molecule is a passive biomarker of tolerance.
Along these lines, during the last decade, significant efforts have been made among the transplant community (Reprogramming the Immune System for Establishment of Tolerance and Indices of Tolerance) in Europe [11] and (Immune Tolerance Network) in the US [12] to identify biological signatures of "operational tolerance".
This interaction allows the establishment of tolerance to luminal antigens.
Although that exposure was without adjuvant, establishment of tolerance to OVA is expected.
"Our clinical development program will allow us to further examine the role of antigen-specific T cells in celiac disease activation and in the re-establishment of tolerance to gluten".
In the EAE model, continuous rhIGF-1 delivery produced clear amelioration even after the antigen response was triggered, presumably due to blockade of autoimmune progression and re-establishment of tolerance.
These data suggest that a short course of Otelixizumab resulted in long-term immunological modulation, supporting data from experimental studies demonstrating that anti-CD3 therapy can result in the re-establishment of tolerance to self-antigens (7, 8).
Since autoimmunity is characterized by the loss of tolerance toward self-structures [ 7], drug-free remission at the molecular level probably means not only complete suppression of disease activity, but also the re-establishment of tolerance.
