Its structure and expression are discussed with special reference to the establishment of boundary conditions and the importance of rendering the variables and parameters dimensionless.
RITA induces a p53 response in UKF-NB-3 cells but not in the RITA-adapted UKF-NB-3 sub-line UKF-NB-3rRITA10 μ M indicating that development of resistance to RITA resistance involves the establishment of mechanisms that render RITA-resistant cells insensitive to RITA-induced p53 activation.
Even though those promises are attractive, there are limits: (i) many traits are polygenic and can be under the control of many genes with minor relative effects, rendering the establishment of conservation measure solely based on genomics a complex task (Harrisson et al. 2014).
Many argue, conversely, that the end aim of Israel's settlement policy in the West Bank is to render the establishment of a viable Palestinian state impossible.
The wide variation of water and sediment geochemistry along a flow path renders the establishment of background metal values difficult.
This is crucial for a functional RNAi pathway and establishment of heterochromatin in S. pombe, as mutations rendering Dcr1 cytoplasmic abolish siRNA generation and the methylation of H3K9 (Emmerth et al, 2010).
It has also interpreted the constitutional prohibition of the establishment of a state religion to render school prayer and religious instruction illegal.
However, by a combination of weak growth, asynchronous flowering with the maize crop, low resistance to frost, low competitiveness, absence of a dormancy phase, susceptibility to diseases, herbivory and cold climate conditions survival of the plants is estimated to be unlikely, rendering the risk for outcrossing and establishment of populations limited [3, 9, 10].
Unrest in Turkey is the manifestation of a defunct political opposition, and the final stand of secular, liberal, and nationalists groups, rendered powerless in parliament, to preempt the establishment of an AKP democratic-dictatorship.
