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The results confirmed the successful establishment of rat glioma model.
These materials were proved successful for establishment of rat pheochromocytoma cell (PC-12), Human neuroblastoma cells (SH-SY5Y), Human epithelial carcinoma cells (HeLa), and Human embryonic kidney cells (HEK-293T) on the metal electrode surfaces [3, 4, 10, 11].
Based on recent studies showing that inhibition of differentiation inducing signals is essential for derivation and establishment of rat ESCs [14], [15], we speculated that the same treatment may be necessary for rat iPS cell maintenance.
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After successful establishment of a rat OP model, we found that ASCs from OVX rats exhibited a comparable proliferation capacity to those from NORM rats but had significantly higher adipogenic and relatively lower osteogenic potential.
The establishment of the rat model of pulmonary tularemia is especially attractive for the screening of defined vaccine candidates, given the similar sensitivity of the rat to the various F. tularensis strains as humans.
The establishment of DCM rat model was verified by fasting blood glucose concentration and impaired cardiac function (Fig. 4D).
After successful establishment of the rat model for CRC liver metastases, we investigated the effects of PH on tumor cell growth.
After the establishment of endotoxemic cirrhotic rat model was determined, follow-up tests were conducted.
This group has funded a number of model systems to further research, including the development of a high content screen of over 25,000 compounds for CMT1A (PMP22) and CMT1E (point mutation), the establishment of transgenic CMT1A rat models, a CMT2A (mutationation) mouse model for testing therapeutics, and a CMT2A zebrafish model for screening.
Furthermore, the time point of study (6 weeks after diabetes induction) was shorter than optimal for the establishment of DN in rats, and the histologic sections provided are of inadequate quality, falling short of establishing DN changes.
The main advantages of the well-established CCl4 model include convenience and establishment of both mouse and rat models with evidence of fibrosis/cirrhosis across routes of CCl4 administration.
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