Sentence examples for establishment of origin from inspiring English sources

Besides, factors involved in the establishment of origin timing such as histone deacetylation induce local modifications in these key origin features, leading to a more open origin conformation.

The semi-quantitative results were then submitted to statistical evaluation, namely principal component analysis (PCA) for the establishment of geographical origin discriminations.

This analytical approach should permit identification of lesional anatomical subsites, establishment of lesional origins, and allow for an anatomy-based differential diagnosis.

Establishment of parent of origin-specific DNA methylation at the ICR occurs during gametogenesis and the zygote either inherits a methylated allele from its mother or from its father at fertilization.

Although FKH1 and FKH2 are not required for origin licensing, the binding of Cdc45 to early origins in G1 seems to be Fkh1/2-dependent, and it has been suggested that the role of Fkh1/2 in origin firing would involve the establishment of replication timing domains and the spatial organization of origins [ 11].

The ecological context of infections is often neglected; yet to understand the establishment of infections the origin of pathogens has to be considered.

Establishment of a depletional origin of hyponatremia is not always easy particularly in the medical ward [ 35, 36].

This was followed by a paradigm shift with the establishment of a tubal origin of most HGSC.

In our case, seven months elapsed between the detection of the oral metastasis and the establishment of its gastric origin, possibly because of an initially incorrect interpretation of the clinical history and histopathological features.

82 Loss and reacquisition of DNA methylation occurs during specific phases of germ cell development, and probably represents erasure of the imprint from the previous generation and re-establishment of the parent-of-origin specific epigenotype.

These observations together suggest that H3K9 methylation plays an important role in the establishment and maintenance of parent-of-origin-specific imprints through a variety of mechanisms.