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Architectural proteins orchestrate higher-order chromatin organization through the establishment of interactions between regulatory elements across multiple spatial scales.
This composition of CALM permits the establishment of interactions during clathrin-coated pit assembly.
Furthermore, we will evaluate a set of biological parameters extracted from the literature in order to help with the establishment of interactions in the networks.
The "omic" data have been widely used in the establishment of interactions among small molecules, genes and diseases and the identification of molecules specifically associated with certain pathological processes [ 66– 66].
Here, we have demonstrated that the establishment of interactions between the diverged regulatory networks in allopolyploids is accompanied by massive homoeolog-specific up- and down-regulation of gene expression.
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The establishment of interaction network also enables the integration of the intricate regulatory circuitries that regulate telomeres with other cellular machinery.
We hypothesize that active partner selection may also play a role in the establishment of interaction specificity, as neither temporal nor geographical isolation seem sufficient explanations to arrive at the levels of specificity observed.
It has been further suggested that short sequence separations may be preferred for the establishment of stable interactions for the design of novel artificial enzymes and the modification of slow-folding proteins with aggregating intermediates.
Molecularly imprinted polymers (MIPs) for the recognition of proteins are expected to possess high affinity through the establishment of multiple interactions between the polymer matrix and the large number of functional groups of the target.
Thanks to the establishment of acid base interactions, pAcDED-coated MNPs were able to load and release significant drug amounts resulting in good antimicrobial properties versus Staphylococcus epidermidis (MIC = 0.1 mg/mL).
Altogether, these data suggest the establishment of complex interactions in Leishmania-HIV common natural host cells [56].
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