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Toll receptors were initially found in Drosophila as an important protein family which plays roles in dorso-ventral establishment of developing embryo and Pathogene-Associated Molecular Patterns (PAMPs) recognization for preventing fungal infection[9], [10].
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It is therefore likely that sleep-dependent protein synthesis plays critical roles in the initial establishment and refinement of developing synaptic circuitry.
These fibre structures are usually not observed when analysing VGLUT2 protein immunoreactivity in the adult brain, where it is exclusively presynaptic and vesicular, suggesting that VGLUT2 is present in the embryo already during the establishment of the developing axonal structures.
Identifying patients at risk of developing chronic pain is a prerequisite for establishment of prophylactic initiatives.
However, there is already an over-capacity in global space industry and there are doubts on necessity of additional capacity establishment by developing countries.
With the recent growing increases of wireless devices, radio spectrum scarcity occurs and mandates the establishment of methods for developing technical description to access efficiently the available radio spectrum.
Establishment of cohorts in developing country setting have unique challenges which differ between locations and populations.
The JNA laid emphasis on the need for development efforts to be focused more on state building by strengthening existing institutions and supporting the establishment of new ones, developing policy frameworks and strategic programmes, putting in place enabling legal and regulatory frameworks and building capacity to implement, monitor and adjust policy.
"But reform outside the government and the establishment is developing".
Enshrined in his later years as the revered patriarch of the literary establishment, he developed a habit of downplaying to the point of suppression what he called his "juvenile errors", much as, in the past century, youthful flirtations with communism or fascism have often become a source of middle-aged embarrassment.
The comparison with experimental data suggests a faster establishment of the fully developed flow.
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CEO of Professional Science Editing for Scientists @ prosciediting.com