Sentence examples for establishment of cohesion from inspiring English sources

Sister chromatid cohesion is established during S phase by the Establishment of Cohesion protein, ECO1/CTF7 [ 14- 18].

Upon entry into S-phase, as the sister chromatids are being synthesized, the two establishment of cohesion factors, ESCO1 and ESCO2, establish cohesion by securing the cohesin ring around sister chromatids (Skibbens et al., 1999; Hartman et al., 2000; Homer et al., 2005; Skibbens, 2009; Terret et al., 2009).

Studies in yeast indicate that tethering of sister chromatids is established at the replication fork and requires the activity of Eco1 (establishment of cohesion 1) acetyltransferase, which is essential for viability in yeast (Uhlmann and Nasmyth, 1998; Skibbens et al, 1999; Toth et al, 1999; Lengronne et al, 2006).

Thus, the establishment of cohesion between sister chromatids appears to be regulated, directly or indirectly, by a specific acetyltransferase.

Since our data are comparable with those of Kenney et al., we propose that in human cells, as in Xenopus egg extracts, cohesin is dispensable for the establishment of cohesion and that cohesion can be maintained at the centromere by DNA catenations at least until metaphase plate formation.

In addition, Eco1 is important to maintain sister chromatid cohesion after the introduction of double strand breaks in G2/M phase of the cell cycle [5] [7], suggesting that the establishment of cohesion is also essential for postreplicative repair of double strand breaks.

Furthermore, cross-training can foster a sense of a shared "common bond" (Greenbaum 1979, as cited in Blickensderfer et al. 1998) amongst team members and support the establishment of morale, cohesion and confidence.

Establishment of stable cohesion involves acetylation of the Smc3 component of cohesin during replication by the Eco1 acetyltransferase.

The conclusion that mutations like scc4 m35 affect establishment of centromeric cohesion through a Chl4-dependent process is not rigorous.

In addition, decreased inter-sister-chromatid distances were observed after DSB induction in chicken DT40 cells, consistent with the establishment of DI cohesion [ 43].

We found that BAF180 is important for the establishment or maintenance of cohesion on chromatin at centromeres.