Sentence examples for establishing the activity from inspiring English sources
The main findings show the role of the products type in determining the benefit of establishing the activity levels.
Despite the fact that clinical trials establishing the activity of these agents in RCC represent landmark studies, between a third and two-thirds of patients (depending on prognostic factors and clinical setting) have intrinsically resistant disease and do not benefit from treatment with agents such as sunitinib or everolimus.
Phase one involved establishing the activities and outcomes clinicians viewed to be associated with these posts through a three round Delphi method.
Some participants described a sequence of events in which one activity lead to subsequent events that culminated in a fall, which made it difficult to establish the activity at the time of the fall.
Here we establish the activity of voreloxin as a first-in-class topoisomerase II poison and inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis.
Phase II clinical trials established the activity of trastuzumab as single-agent in Her2-positive metastatic breast cancer [ 9, 10].
The study was placebo-controlled in order to definitively establish the activity of pazopanib, and provided placebo subjects the opportunity to crossover to pazopanib upon progression.
However the sIL-2R measurement revealed a crucial advantage to establish the activity of IM when CK levels are persistently elevated.
According to Simon's optimal two-stage design more than 18 ORs out of 54 patients were required to establish the activity of this regimen.
This Phase II study established the activity of axitinib in patients with clear cell RCC refractory to conventional VEGF-inhibitor therapy.
Using our multi-compartment model, we (i) established the activity distribution of APP in various compartments, and (ii) traced the activity distribution of APP, α-secretase, β-secretase and SORLA in the monomeric and dimeric processing of APP.
