Sentence examples for establishing proof of from inspiring English sources

He argued against approving the settlement in hopes of establishing proof of coverage that could yield higher payments.

A wide variety of catalytic transformations have been established by artificial metalloenzymes, thus establishing proof of concept.

Biomechanical tissue testing and finite-element modelling should complement each other, with experiments establishing proof of concept, and models supplying detail and optimising designs.

Establishing proof of the actions of a bad leaver or rogue employee can rapidly remove any doubt about their motivations, and claims of innocence or of a simple misunderstanding.

The Chorus model can help companies improve the efficiency of their innovation processes by establishing proof of concept early and reducing project attrition downstream, particularly in the later and more expensive phases of drug development.

Medicinal chemists at TDI whose contributions she calls "priceless"—are helping to develop compounds to block the molecular pathways that cause these vessels to leak, with the goal of establishing proof of concept in a mouse model.

We are establishing proof-of-principle for human or mouse organoid transplantation, ultimately to effect phenotypic correction of diseases.

We also describe the role of PD analyses in clinical trials, including for MOA confirmation and dosage regimen optimization during phase 0 trials as well as for correlating molecular changes with clinical efficacy when establishing proof-of-concept in phase I/II trials.

Therefore this novel line may provide a useful additional model for establishing proof-of-concept for new therapeutic concepts.

Here we achieved increased gene delivery by transgenic overexpression of CAR, a strategy that is suitable only for establishing proof-of-concept in animal models.

This study evaluated masitinib using in vitro and in vivo models of human pancreatic cancer, both as a single agent and in combination with gemcitabine, with the objective of establishing proof-of-concept.