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Within this process, two methods for decomposing functions, which are conducted in the establishing of function structures, will be explained: the method of focusing on logical relationships among partial functions and the method of dividing flows related to energy, material, or signals.
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To that end, we established loss-of-function (LOF) and gain-of-function (GOF) strategies to interfere with sprout formation.
As a first step to establish gain-of-function approaches, we asked whether adenoviral mediated overexpression of Vps15 and/or Vps34 in Vps15-deficient MEFs was sufficient to rescue the autophagolysosome defects.
It often takes the form of staged images in which she challenges established concepts of function and material.
Knowledge of the role PTH/PTHrP system in early vertebrates will help to establish evolution of function.
As Ponting and Belgard have pointed out [ 9], established tests of function that depend on gene knockout or overexpression only work for a fraction even of known protein-coding genes.
A World Health Organization initiative to establish International Classification of Functioning, Disability and Health ICFF) 'core sets' for specific conditions pursues much the same goals [ 10].
This, and other strain sets, facilitated a wide range of systematic studies aimed at establishing the function of the genes, e.g. [ 4- 8].
The E124A and R135A alleles retained tgs1 ∆ suppressor activity, thereby establishing a separation-of-function.
The above researches mainly focused on establishing component function of outage probability or outage rate that using operating conditions as the independent variables.
PGCs are lost by apoptosis in the absence of Nanos3, establishing an essential function of Nanos3 as a repressor of apoptosis in the germ cell [ 34].
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CEO of Professional Science Editing for Scientists @ prosciediting.com