Exact(1)
In the era of targeted therapy, the assessment of Akt activity in tumours will move from determining its importance in the genesis of cancer to establishing its activity in individual tumours as a means of defining targeted treatment.
Similar(59)
This is exemplified by the functional signature of the plasmid shuffle strain discussed above; given any new high-throughput dataset, microarray or otherwise, we provide a means for establishing its functional activity in the context of existing data.
Limonin administration establishes its anticancer activity by totally refurbishing the smashed hepatocytes in Group III animals.
In the present study, we document to explore an approach to conjugate gold nanoparticles (GNPs) with protein toxin (NKCT1), a protein toxin from the Indian cobra (Naja kaouthia) venom, and to establish its antileukemic activity.
Thus, C. sanguinolenta is a potential medicinal plant that must be investigated to establish its antimicrobial activity.
Further detailed clinical trials and studies will be necessary to investigate what components in E. alba extract contribute to its efficacy, since whole E. alba extract, rather than individual components, was used here to establish its biological activity against alopecia.
Folk Indian medicine refers to the use of leaf and stem bark powder of Tabernaemontana alternifolia (Roxb) in treatment of skin infections, but no scientific report establishes its antibacterial activity.
This was used to transfect Sf9 cells, yielding modest amounts of a 22-kDa protein after 72 h, and partial purification of the protein was necessary to establish its biological activity [ 105].
EEP was diluted in sterile, pure DMSO and then tested at a concentration of 50 μg/mL (reference solution) to establish its cytotoxic activity on SF-295, OVCAR-8 and HCT-116 cell lines.
The in vitro antimicrobial screening of Gymnema sylvestre leaves against 13 test pathogens established its broad spectrum activity with average inhibition zone ranging from 14 to 23 mm.
Further studies to establish its clinical antitumour activity are currently being considered.
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