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In recent years, our research group has formulated a new framework called materials knowledge systems (MKS) for establishing highly accurate reduced-order (surrogate) models for localization (opposite of homogenization) linkages in hierarchical materials systems.
Transmissible Spongiform Encephalopathies (TSEs), a member of the protein misfolding diseases (ex: Alzheimer's and Parkinson's Diseases), were chosen as the infectious agent for this study because they rank as the hardest to kill microbe/pathogen, affect both human and animal species worldwide and are shed by infected hosts into the environment establishing highly infectious biota.
Ezrin, and its close relatives, radixin and moesin (the ERM protein family), are typically involved in establishing highly motile and very narrow structures in the CNS, such as neuronal growth cone filopodia [47], [48] or peripheral astrocyte processes [49], [50].
Together, these results suggest that ire-1 is required for establishing highly branched dendrites.
Cellular factors other than equine MHC class I might be required for establishing highly efficient infection of NIH3T3 cells with EHV-1.
One of the holy grails of modern medicine, across a range of clinical sub-specialties, is establishing highly sensitive and specific biomarkers for various diseases.
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For the establishment of this method and its further application it was essential to establish highly reproducible transient transfections in a cell line which showed sufficient viability in the Bionas system for long-term kinetic experiments.
Ms Hodge said big accountancy firms were also culpable: "This committee has vigorously condemned the activities of the big UK accountancy firms in helping their clients find loopholes in legislation and establish highly artificial tax structures.
Far from being a "tax haven," Bermuda has helped the reinsurance industry develop excellent best practices, innovate to better serve customers and establish highly regarded enterprise risk management programs.
The Centers for Disease Control and Prevention has established highly specific criteria for the diagnosis of Lyme disease: an acknowledged tick bite, the appearance of a bull's-eye rash, and, for those who don't live in a region where Lyme is common, laboratory evidence of infection.
Therefore, it is necessary to establish highly efficient and reliable methods for the cryopreservation of hES cells.
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