Sentence examples for establishing gene expression from inspiring English sources
These factors play key roles in establishing gene expression patterns that dictate cell-type specific functions and characteristics.
This new platform is publicly available at the following web address: http://resource.ibab.ac.in/MGEx-Tdb/ Establishing gene expression patterns would facilitate understanding of almost every aspect of cellular and molecular biology.
The synthesis of full-size L1 RNPs in mitotically dividing cells appears to be strongly implicated in establishing gene expression profiles characteristic for totipotent/pluripotent and poorly differentiated cells.
Most of the genome-scale studies on DNA methylation have focused on CpG islands (CGIs) or gene promoters (e.g. Borgel et al).. Currently, the importance of DNA methylation of other parts of genes, non-genic or intergenic regions for establishing gene expression and the nuclear organization of chromatin is increasingly recognized.
Our data point towards a model for gene regulation in which not only are the post-translational modifications of histones essential for establishing gene expression patterns, but equivalent modifications in DNA-binding transcription factors are also an integral part of whatever 'code' underlies these patterns.
To establish gene expression profiles, differentially expressed probe sets in the pair-wise comparisons were identified using the Kruskal-Wallis test.
An emerging strategy to fight cancer complexity is to establish gene expression profiles and connect them to specific signaling pathways contributing to the disease [3].
The hypermethylation mark may in some cases, be laid down subsequent to transcriptional down-regulation of a gene [28], but experiments using the DNA methyl-transferase inhibitor (5'-deoxyazacytidine) show that de-methylation of a specific gene promoter can re-establish gene expression [21], [29].
36– 39 These diagnostic assays were developed using established gene expression analysis approaches.
We also expressed wild-type and mutant WT1 proteins in human mesenchymal stem cells and established gene expression profiles.
In order to establish gene expression profiles for both CAN nucleases we analyzed microarray experiments reported by Genevestigator [ 29].
