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There are four important stages in the design process: clarifying objectives, establishing functions, setting requirements, and improving details.
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Establishing function for some of these predicted transporters may require alternative genetic, biochemical, or physiological analyses.
The "protein first" model of RNP argues that proteins with established functions scavenged non-functional or duplicated RNA transcripts for better or modified substrate specificity.
In a lot of his work, he's saying that men and women have established functions in the social order.
This can be achieved by creating electrically conducting geosynthetics and combining electrokinetic functions with established functions.
Productisation has implications through having a complementary role amongst well established functions and in strengthening the linkage of market needs and engineering-oriented development.
Two of these are Amphiphysin and Caveolin, which both have established functions in membrane dynamics [49], [50], [51], [52].
In contrast to these established functions in intestinal pathogenic E. coli, roles for T2SS and T4P in the virulence of ExPEC have not been established.
Established functions have been previously assigned for several of these differentially expressed genes (Table 3).
FA proteins have well established functions in repairing interstrand crosslinking (ICL) lesions (Kee and D'Andrea, 2010).
Established functions for mTORC1 are to phosphorylate 4EBP1 and activate S6-kinase, which in turn phosphorylates the S6 protein [ 13].
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