He dramatically modernized Denmark's state administration, establishing, for example, colleges for the various branches of government.
Through the temporal dissection of aberrations, we identified driver mutations specifically associated with steps in the progression of prostate cancer, establishing, for example, loss of CHD1 and BRCA2 as early events in cancer development of ETS fusion-negative cancers.
Doctors say that studies of Arava have also shed new light on the treatment of rheumatoid arthritis, establishing, for example, that patients need powerful therapy in the disease's earliest stages to help protect joints from irreparable damage.
Considerations of this kind much reduce the evidential value of discoveries establishing, for example, that the number of graves in Attica and the Argolid (the area round Argos) increased dramatically in the later Dark Age or that there was a serious drought in 8th-century Attica (that is the admitted implication of a number of dried-up wells in the Athenian agora, or civic centre).
In classical mathematics, he founded modern topology by establishing, for example, the topological invariance of dimension and the fixpoint theorem.
Modeling of the system can be at a micro level, i.e., modeling the effect of stresses into the material by establishing for example a finite element model.
It has helped establish, for example, links among the recent sniper murders in the Washington suburbs.
He helped establish, for example, that senility is not inevitable with aging.
It is well established, for example, that a bout of strep throat can set off rheumatic fever, an autoimmune disorder.
After high-speed trains between Paris and Lyons became well established, for example, commercial flights all but disappeared.
