The first proof-of-concept trial established activity of the AR antagonist, bicalutamide, in patients with advanced AR+ triple-negative breast cancer.
On the basis of the above data, the established activity of ifosfamide+ciplatin and the favourable preliminary results of the paclitaxel+carbolatin combination, in 2001, we elected to evaluate the combination of TICb in advanced MMMTs.
The behavior of BPA in this system is consistent with the established activity of BPA as an estrogen receptor agonist (reviewed by vom Saal and Hughes 2005; vom Saal and Welshons 2006; Welshons et al. 2006), which was first reported in 1936 (Dodds and Lawson).
In addition to the well established activities of the sirtuins, "long chain" acyllysine modifications were also shown to be prone to hydrolytic cleavage by SIRT1-3 and SIRT6, supporting recent findings.
In order to establish activities of the Spy variants their influence on the refolding yields were related to the activity shown with wild type Spy.
Further, they establish a stronger transcriptional activity of the let-7-C promoter in the testicular soma compared to the activity in the ovarian soma.
We placed the Thunder tool into an established activity system of student presentations in University-level Architecture education and examined how that system was re-mediated by participants' use of the tool.
56 TMZ has established activity in the treatment of rGBM and rAA patients.
This method provides an enabling platform for establishing functional activity of topically applied products.
The cytokine response, LPS uptake, and established antimicrobial activity of WLBU-2 demonstrate modulation of proinflammatory signaling as a protective mechanism to clear infection.
