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Taken together, this establishes the notion that anchors being mainly hydrophobic have a higher propensity for membrane insertion than the functional TM-helices since the latter are enriched with charged and structural residues.
Essentially, this basis establishes the notion of simple (implying convergent evolution) and complex (implying common ancestry) TM helices in nature and, hence, the possibility of their separation with computational criteria.
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Entebbe had helped establish the notion that Israel's reach was simply too long for it to be defeated militarily.
The civil rights movement firmly established the notion of bias as unconscious prejudice, to the point where the protestation "I'm not biased" came to sound suspect.
He must first re-establish the notion that if you work hard and play by the rules in America you will get ahead in life.
Welles established the notion of the epochal first feature that didn't just launch a career but knocked the history of cinema into a new orbit.
As newsprint becomes a smaller part of the business, "you want to establish the notion that it's worth something online," Mr. Brill said.
In his influential 1550 work, "Lives of the Artists," the historian Giorgio Vasari, an ardent patriot of Tuscany, established the notion that Giotto single-handedly melted the frozen forms of Byzantine art.
WHILE Defoe may have established the notion of what an island should be, the author Clarke quotes most frequently on what islands are becoming is George Orwell, who wrote "Nineteen Eighty-Four" in a farmhouse on Jura, in the Inner Hebrides.
This work was primarily an attempt to establish the notion of duration, or lived time, as opposed to what Bergson viewed as the spatialized conception of time, measured by a clock, that is employed by science.
It established the notion of an "independent counsel", legal protections for whistleblowers, the Fair Campaign Practices Act, the Privacy Act of 1974 and a beefed-up Freedom of Information Act.
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