Sentence examples for established with confidence from inspiring English sources

Unless full PK/PD relationships can be determined, the drug target candidate profile for first in class targets cannot be established with confidence; consequently, chemistry strategy cannot be implemented without risks.

However, the phylogenetic relationships among the tested isolates determined from different methods of analysis are not always consistent and could not be established with confidence.

Because of the cross-sectional nature of the study, the temporality of certain associations cannot be established with confidence.

Specifically, an enhancing stalk is seen in many polyps, allowing the diagnosis to be established with confidence (Fig. 7).

Few relevant differences could be established with confidence in unigenes potentially specific for roots, probably owing to their significantly smaller number, likely determined by the considerably smaller number of reads obtained from this tissue.

Moving forward, we encourage the evaluation of the relative success of barcoding in an explicitly phylogenetic context, where the relative relatedness of the species being sampled can be established with confidence.

"There is, inevitably, further work for my colleagues and I to do to evaluate those submissions, which are detailed and substantial, in order to establish with confidence the time needed to complete the Inquiry's remaining work," he said.

Thus, a suggested area of research is on how to use robust experimental evidence to establish with confidence the impact of subsidized health insurance programs on informality and health.

Thus, a suggested area for research is on the way to use robust experimental evidence to establish with confidence the impact of subsidized health insurance programs on labor informality and health.

For example, when the value of a monosomy (or ChrX in a male patient) establishes with confidence the continuous log2 value corresponding to discrete integer copy loss, this signal is often an arm-length loss that falls halfway between diploid and the log2 value of single-copy loss.

Therefore, it is currently unfeasible to establish with confidence the degree to which specific NMDRs are reproducible.