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It has to be established whether the level of inhibition of FTase that was seen in PBMCs in this trial will translate into meaningful antitumour activity.
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To assess associations between uCTX-II or uCIIM and severity of hip pain in patients with mild-moderate hip osteoarthritis (OA) over a 2-year period, and establish whether the level of these biomarkers at baseline could estimate a specific trajectory of hip pain.
In the absence of measurement invariance, researchers are unable to establish whether the level of body dissatisfaction experienced during pregnancy is commensurate with, or perhaps greater than, that reported pre-pregnancy.
Multiple linear regression analysis was performed to establish whether the levels of BMI and EF affect Crs.
It remains to be established whether the lower levels of circulating plasma estradiol are responsible for the changes in the diabetic rats.
The authors report that a large body of preclinical experimental work has demonstrated the high sensitivity of prostate cancer to the protective action of ω-3 PUFAs, while in contrast it has not been definitely established whether the ingestion of increased levels of these fatty acids may actually have a protective effect in prostate cancer patients.
Although some miRNAs have been shown to exert a disruptive effect on skeletal muscle differentiation at least in cell culture models [ 70], in most cases, it remains to be established whether the changes in miRNA expression levels are causally involved in these diseases or are secondary to the degeneration/regeneration response of the affected muscle tissue.
To address this question, it will first have to be established whether the observed changes in miRNA expression levels due to environmental exposures are the result of a direct effect or a surrogate indication of a different mechanism.
We established whether the researchers belonged to our organization and collected details regarding their license level.
To establish whether the CLU levels found in this study were in agreement with previously reported data, we developed a method for absolute quantitative analysis.
Next, we wanted to establish whether the increased levels of GRP75/Mortalin and Calreticulin, observed to correlate with disease progression in SMA mouse models, were also measurable in skeletal muscle from human SMA patients.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com