Sentence examples for established well over from inspiring English sources

The association between estrogen and breast cancer was established well over 100 years ago (Beaston 1896).

The systemic inflammatory effects of acute lung injury were established well over a decade ago [ 8]. 'Biotrauma' - as this phenomenon has been termed - provides the mechanistic basis for the mortality benefit of lung-protective ventilation demonstrated in the ARMA trial [ 9].

With support from various governmental and non-governmental grants and contracts, our faculty have established well-recognized laboratories that are distributed over 25,000 square feet of dedicated space.

Click here for additional data file.. Widespread mis-regulation of the expression of disomic genes in trisomic genomes has been established for well over a decade (and seems a self-evident outcome of a trisomy such as that of Hsa21 which includes eight transcription factors, 29 microRNAs and a large number of lncRNAs among other key regulators).

It is well established that over-enforced expression of wild-type proteins can cause a mutant phenotype due to competition with other macromolecules and/or non-functional subassemblies/disassembly's, leading to a reduced function of the protein70.

2) It is well established that over-expression of miRNA can repress target mRNA and that over-expression of a miRNA sponge can de-repress a miRNA target.

It is now well established that over-distention of the alveoli can damage alveolar lining cells and result in local and systemic inflammatory immune responses that can be deleterious to the host, even in the absence of pulmonary infection [ 2].

While the negative effect of shorter birth spacing on neonatal and infant mortality as well as maternal health is well established, over a fifth of Ethiopian women are currently giving birth within 2 years of a preceding birth and 16% have an unmet need for child spacing [ 9].

It is well established that over his professional career Mr. Olbermann has specialized in pounding the table.

It is well established that over the last decade the seasonally migrating creatures at the top of the economic food chain have turned the pursuit of contemporary art into a defining marker of wealth and social status.

That crime is concentrated at a few places is well established by over 44 studies.