14 16 20 21 Since there is no established, well-documented treatment to which new treatments can be compared, the use of a control group is important.
Prediction of the evolution of rail (and wheel) profiles using design tools that integrate multi-body dynamics (MBD) simulations of track and rail vehicles with tribological models of material removal are well established and well documented.
While the study of the catalytic kinetics of enzymes represents one of the most established and well documented fields in biochemical research, the impact of biochemical state (pH, ionic strength, temperature, and certain cation concentrations) is typically not formally accounted for in kinetic studies [1], [2].
Both interventions are established and well documented procedures.
The polymorphism had some degree of likelihood to alter the structure or the expression of the gene in a biologically relevant manner (i.e., affecting ESE sequences, 3′-UTR or promoter region); The minor allele frequency was above 10% (with the only exception of rs2305948, rs6877011 and rs307822); and The genetic polymorphism was established and well documented.
The antitumour activity of flavone acetic acid (FAA) against a range of transplantable murine tumours with established vasculature is well documented (Plowman et al, 1986; Smith et al, 1987; Hill et al, 1989) and appears to be related to the production of tumour necrosis factor-alpha (TNF- α), since antibodies to TNF can prevent the reduction in blood flow caused by FAA (Mahadevan et al, 1990).
It is important to simultaneously establish a substantial base of well documented interventions and additionally create strategies for successful knowledge transfer.
The ACG index (RI) used as an indicator of morbidity burden was selected for two reasons: First, it is well established, internationally validated, and well documented for use in risk calculation [ 11, 14].
Their benefit in reducing cardiovascular events and mortality after an acute coronary syndrome, as well as the reduction in risk of major cardiovascular events in people without established cardiovascular disease is well documented.
1 3 The hazardous health effects of exposure to SHS are well documented and established in various independent research studies and numerous international reports. 1 4 Scientific evidence has unequivocally established that SHS causes premature death and disease.
With the role of the internet in helping new acts from Arctic Monkeys to Enter Shikari rise to prominence already well documented, more established artists are attempting to revolutionise the way music is sold.
