Sentence examples for established vaccines from inspiring English sources

Introduction: With the advent of new vaccines, improvements in established vaccines, and the availability of new combination vaccines, parents' decisions about vaccinating their children have become more complicated.

Current batch release testing of established vaccines emphasizes quality control of the final product and is often characterized by extensive use of animals.

As perceived risks vary with uncertainty, it cannot be assumed that findings from studies on attitudes about established vaccines for existing diseases can be extrapolated to pandemic situations.

Secondly, for established vaccines, PMS aims to monitor known adverse reactions and if the observed rate exceeds the expected rate, further investigation is required.

Nevertheless, regardless the technical, cultural and financial challenges, systems biology applied to vaccinology represents a primary way to go in order to develop novel vaccines and to re-develop established vaccines, switching from the "empirical" to the "knowledge-based" age of vaccinology.

A mathematical model, with immunogenicity parameters derived from a database of human responses to established vaccines, was used to predict the increase in the efficacy and the proportion of the population protected resulting from addition of further immunogens.

Delivery devices using liquid vaccine formulations are advantageous, as established vaccine formulations can be used as provided without the need for reformulation.

During its remarkable journey from conception and design in the early 1980s to the multicenter Phase 3 trial currently underway across sub-Saharan Africa, RTS,S has overcome tremendous challenges and disproved established vaccine paradigms.

Although several studies have established vaccine efficacy into adolescence, most are in Asia where the predominant HBV serotypes differ from those in Africa and some 40% of chronic infection is acquired perinatally from the mother, whereas in Africa child-to-child transmission predominates [ 22- 24].

Moreover, our finding that nanoencapsulation improves antigen stability in MNs for a prolonged period at ambient temperatures provides a strong rationale to study the potential of this technology to increase stability of established vaccine antigens at ambient temperatures, thereby obviating the requirement for cold storage.

This is a vital part of establishing vaccine safety and should be encouraged.