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The original correlation between venom apparatus and molecular phylogeny was established using only western Pacific species [16].
Concordance of responses was established using only surveys in which the two questions required to establish concordance were answered.
Three FeNO reference equations (for males, females, and total sample) were established, using only previously correlated factors in a stepwise linear regression model.
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The diagnosis of acute TBE is hard to establish using only a single serum among patients with prior vaccination.
A direct, requiring no additional technological stages, emulsification process was established using herbal ingredients only.
While the link between genotoxic stress and hair graying has been established using mouse models, only correlative data from human patients are available in regards to life-long UV exposure and hair loss [ 40, 45].
The DIM set was established using sequence alignments only, thus there is a greater chance that DIMs contain false positive mutations arising from either alignment artefacts or sequencing errors in duplications.
One may suspect that the enrichment of miRNA targets may be only established using the current version of miRNAs and these tendencies might disappear with the identification of more miRNAs.
As miRNA target prediction algorithm is known to contain both false positives and false negatives, and our in silico pathway enrichment analysis is based on mRNA genes predicted to be targeted by circulating miRNAs, a full understanding of the potential functional role of circulating miRNAs can only be established using functional experiments.
Nonetheless, the ultimate "gold standards" for gene expression during bovine pre-implantation development can only be established using naturally ovulated/developed oocytes/embryos.
Whereas clinical utility can only be established using much larger and unselected population samples, studies like ours can offer important clues regarding the correspondence between infant early laboratory measures and later clinical outcomes.
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