Sentence examples for established to target from inspiring English sources

Second, new mouse models should be established to target the remaining components of the SCF E3s, including all 69 F-box genes, for tissue-specific Tg expression (gain-of-function) and KO (loss-of-function), ideally in an inducible manner.

Despite the high incidence of KRAS mutation and its correlation with unfavourable prognosis in lung adenocarcinoma (Mascaux et al, 2005), no effective therapeutic strategies have been established to target this subtype of tumour.

An important future direction will be characterisation of the isotypes (IgM, IgG and IgG subclasses) of the initial and expanding autoantibody responses in rodent models, as well as human RA and MS. Autoimmune responses are well established to target both native and linear epitopes present in autoantigens [ 20].

Recently, high-throughput typing protocols are established to specifically target the HLA loci via PCR-amplification, followed by deep sequencing [ 25– 27].

Hard handover algorithms are known as break-before-make, which means the old connection is broken from the serving eNodeB before a new connection is established to the target eNodeB.

However, no animal model has been established to test AO targeting human dystrophin exon in vivo systemically.

Thus, this pathway is well established to be a target for antitumor therapy (Kowanetz and Ferrara, 2006).

Recently, several databases of experimentally validated miRNA targets are established to overcome the unreliability of target prediction.

Large marine protected areas are increasingly being established to meet global conservation targets and promote sustainable use of resources.

However, there are currently no benchmarks or targets established to define quality of care for adults and adolescents for most conditions in this primary care setting.

These elements have the required id attribute, and the selects attribute, which establishes to which target padding language elements the corresponding types must be applied.