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As Darwin anticipated, extensive variation among individuals has now been well established to exist at the physical, physiological, and behavioral levels.
Although our findings are contrasting, it is difficult to reconcile the physiological significance of the elevated phosphorylation of a signalling protein (i.e., Akt) that is so distal within the signalling cascade, especially since a non-linear relationship between anabolic signalling molecules and muscle protein synthesis has been established to exist [40].
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Although no such effect has been established to date, if it existed it would be of significance because of the high prevalence of use – there are currently more than 1 billion mobile phone users worldwide (NRPB, 2004).
What problem exists that they were established to address?
The Declaration stated why separation from England was necessary; the preamble proclaims the high purposes for which our Constitution was established and continues to exist.
It was established by, and continues to exist through, donations from members of the public.
Comorbidity in clinical youth populations is more the rule than the exception, yet few established guidelines exist to help practicing clinicians manage complex diagnostic profiles.
A number of established strategies exist to detect genomic instability in cancer.
When speaking with the director of the O.G.S. at the time, I often felt as though I had entered into a dystopic wonderland, where little of what other scientists had clearly established, again and again, seemed to exist.
When concentration camps are established, they are usually said to exist to protect the larger population from some suspect group, or to be part of a civilizing message, or to be a way to restrain some group of civilians from supporting hostile forces.
In a sense it is true that the tribunals are political since the international political will to establish and fund them has to exist before they can get to work.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com