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Subsequent determination of prognosis could be made by using CSC markers, and a revised therapeutic plan could be established to eradicate CSCs and cure the cancer completely.
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Stage III surveillance provides essential input for programmes established to reduce or eradicate diseases and to enhance food safety.
While nanomedicine-based tools for imaging, dosimetry and treatment are potential keys to the improvement of therapeutic efficacy and reducing side effects, radiotherapy is an established technique to eradicate the tumor cells.
But a social inclination toward tax evasion, once established, is hard to eradicate.
House crows have the reputation for being invasive species and, once established, are probably impossible to eradicate due to their behavioural and ecological flexibility combined with their legendary intelligence, which according to the research, appears to rival or exceed that of humans.
But even in the absence of an antiviral immune response, adenoviruses failed to eradicate established xenograft tumors, despite ongoing viral replication [10], [11].
Because attempts to eradicate established invasive phytopathogenic fungi have met little success, the highest priorities should be given to preventing the introduction and limiting the spread and impact of established invaders [9].
Once established, endemicity is difficult to eradicate [ 12- 14].
Importantly CD4+ T cells have also been described to develop cytotoxicity and they are able to eradicate established melanomas [ 39].
Natural killer-like T lymphocytes termed cytokine-induced killer (CIK) cells have been shown to eradicate established tumours in a severe combined immune deficient (SCID) mouse/human lymphoma model.
Once established, biofilms are difficult to eradicate due to the lack of drug penetration, drug inactivation, or physiological state of bacteria within the biofilm [ 5].
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