Sentence examples for established through the generation from inspiring English sources

Also, a role for the E2F1 gene as a tumour suppressor has recently been established through the generation of mice lacking a functional E2F1 allele.

The regulatory role of PLN in myocardial contractility has been established through the generation and characterization of genetically altered mouse models, which revealed a correlation between PLN expression and contractile function [ 58– 60].

Documentation of the content validity of a measure is specific to its context of use, including but not limited to the population of interest, and is typically established through the generation of evidence from qualitative research comprising patients whose clinical and demographic characteristics are similar to those of the patients enrolled in the respective clinical trials.

Content and face validity were established through item generation, as items were created on the basis of a literature review, interviews with women who had recently given birth, and the clinical opinion of investigators.

Thus, three congenic strains were established through rapid generation turnover between 41 and 44 days.

The distinction between equipment and components, established through several generations of electronic technology based on discrete components, is becoming increasingly blurred.

The CA derives from precursors located in the ammonic neuroepithelium, whereas the DG is established through sequential migrations, leading to the generation of a secondary radial glia scaffold and the relocation of neural precursors from the primary dentate epithelium into the DG area (Altman and Bayer, 1990; Li and Pleasure, 2005).

Hyperparasitaemia in the blood-stage model is established through either an increase in the per-generation multiplication rate from 10to1313 or an increase in the initial number of parasites entering the blood stage from 10 to 10. Figure 3 shows the effect of hyperparasitaemia on the probability of resistance emerging when the resistance to the partner drug is present (Pb = 4.84 × 10−6).

For the three EG genomes, inbred lines were established through full-sib mating for eight generations, while the four KM genomes were sequenced directly from isofemale lines that had been maintained in the laboratory for 12 years and therefore passively inbred.

It has been established through early successful preclinical studies on first-generation CAR T cells that the IL13.E13Y zetakine (IL13 zetakine) T cells induced secretion of IFN γ, TNF α, and GM-CSF only in the presence of IL13R α2-expressing tumor cells.

Established through an act of Congress and through generations of political, civic and economic change, Howard has maintained its aura and appeal as the 'Mecca' of HBCUs.