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Experts have advised that centers wishing to offer therapeutic hypothermia outside RCTs should adhere strictly to a trial protocol and have established the substantial resources required to cool neonates with HIE.
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Genetically modified micro-organisms need further assessment for the complete characterisation of the DNA rearrangement and of the final product, in order to establish the "substantial equivalence" with the parental strain.
Articles addressing the importance of particular areas of research and development, congressional acts, government publications, and historical documents can all be used to establish the "substantial intrinsic merit".
Consequently, the Catholic Church did not establish the substantial presence that it had in other South American countries from the time that European colonization began.
It remains to be established whether the substantial differences in glucan accessibility found in this work are caused by variation in the amount and/or the type of either TW or OW.
Findings of this study clearly established that the substantial barriers to accessing health care in Nigeria negatively impact upon child health and survival.
Grown acquisitive with the financial stability that Kevin's fundraising and stewardship had established, the musicians demanded a substantial pay hike.
JF established and performed the pyrosequencing analysis whereas KK established the NGS approach and made substantial contributions to the NGS analysis.
Mr Comey did not indicate whether the FBI investigation had established a substantial link between the couple and the Islamic State in Iraq and Syria (ISIS) armed group.
The Pulitzer Prize board permitted Guardian US into its awards competition the following year, noting that the site "had established a substantial and distinctive presence in the United States with operations in New York".
The promise of positive approaches is clearly supported by established knowledge of the substantial positive influences of good quality work on mental health and wellbeing.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com