Exact(4)
Application of antisense ODN technology has revealed a role for timeless (Tim) in the core clock mechanism and established that induction of period1 (Per1) is required for light responsiveness.
Earlier it was established that induction of IL-6 synthesis may involve different pathways.
As it is well established that induction of colitis in human as well as in animal models requires the presence of bacteria, we set out to study CD14+HLA-DRhi monocytes in patients with chronic intestinal inflammation.
Several groups, including Harding et al. (2001), Feng et al. (2009), and Allagnat et al. (2010), have established that induction of ER stress and the UPR is sufficient to compromise insulin secretion from β-cells in a cell autonomous manner.
Similar(56)
This suggests that, from day 4 onwards, a "transit-amplifying" population of Sox1-GFP+ NPs is established and that induction of new NPs contributes little to the growth of this population.
Since the gene products required for the production and sensing of cAMP are themselves induced by cAMP, a positive feedback loop is established that is required for the full induction of genes that regulate multicellular development [2].
It is well established that the induction of LTP and LTD at the Schaffer collateral-CA1 synapses of the hippocampus requires the activation of NMDA receptors [16], [18].
It is well established that the induction of pro-apoptotic genes (that is, Puma, Noxa etc) is required for the initiation of apoptosis by p53.
Our previous studies established that the induction of cell death in MB cells occurred, at least in part, through the extrinsic apoptotic pathway and mitotic disruption [ 12, 14].
Having established that the induction of DNA modifications can also occur in the cellular compartment, we investigated whether this phenomenon was a peculiar feature of the malten chemical structure.
We also show that induction of brain injury using an established focal ischemia model in the rodent induces profound spatiotemporal-dependent changes of GPR17.
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