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The UN Convention on the Rights of the Child (1989) established that in addition to children's human rights to protection from harm and provision of an adequate standard of living, children also possess civil rights to participate in the cultural and civic activities of their communities.
To develop a firm understanding of the mechanical properties of any given material, it has been established that in addition to understanding the crystal structure, a knowledge of the defect structures and their properties is also essential [1,2].
Alternatively, it is well established that in addition to being the catalytic core of the γ-secretase complex, Psn can also function in a γ-secretase independent fashion [72], [73].
We previously established that in addition to the ½ site p53 RE (−677 from the Transcriptional Start Site, TSS) a ½ site ERE located 225 nt upstream of the p53 RE (referred to as ERE1; −902 from TSS) is required for efficient p53-induced transactivation of the FLT1 promoter [17].
It has also been established that, in addition to the classical model of liganded ER that binds DNA at defined oestrogen response elements, other response pathways can become activated by ER.
Emerging evidence in recent years has established that, in addition to their fundamental roles in chromosome segregation and organization, cohesin and condensin are also required for DNA damage checkpoints and DNA repair.
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Our results confirm previous reports and establish that, in addition to the widespread localization of sense-oriented SIDERs in 3'UTRs, antisense SIDERs are enriched in interstitial regions between polyadenylation and trans-splicing sites.
Our studies further establish that in addition to being biochemically distinct, GBAF and esBAF complexes are differentially targeted on the ESC genome.
In conclusion, the present study establishes that in addition to affecting chondrocyte maturation, Pb accelerates the differentiation of mesenchymal precursors into chondrocytes.
Panels D, E, F, G of Figure 3 establish that in addition to regulation of AC5 expression, PhLP1 also independently affect its activity by releasing Gαs/olf subunits.
To further support the concern for children indicated by our quantitative risk assessment, we cited toxicologic studies establishing that in addition to chloinesterase inhibition, on which the NOAEL for chlorpyrifos is established, chlorpyrifos and chlorpyrifos oxon have other neurodevelopmental toxicity mechanisms (Huff et al. 1994; Qiao et al. 2002).
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