Sentence examples for established that activation of from inspiring English sources

Having established that activation of CD28 enhances the activity of AMG 330 in leukemic cell lines, we aimed to assess whether activation of CD28 also impacted the efficacy of BiTE antibody constructs against primary patient leukemia cells.

Previous work has established that activation of Mos, Mek, and p42 mitogen-activated protein (MAP) kinase can trigger release from G2-phase arrest in Xenopus oocytes and oocyte extracts and can cause Xenopus embryos and extracts to arrest in mitosis.

It is well established that activation of NMDARs plays an essential role in spinal cord synaptic plasticity (i.e., central sensitization) and pain hypersensitivity after tissue injury.

Recent studies in humans established that activation of the UPP is associated with loss of muscle protein in the diaphragm of patients receiving CMV [3, 8].

It has been well established that activation of HSCs plays a key role in the development of cirrhosis [1].

It is well established that activation of AMPK is associated with inhibition of the m-TOR pathway leading to ribosomal protein S6 dephosphorylation [27].

Recordings from striatal neurons of these mice establish that activation of D2-like DRs abnormally inhibits glutamate-elicited currents.

Furthermore we establish that activation of MBF-dependent transcription is critical for cell survival in response to replicative stress.

Using pure cultures of striatal neurons we could establish that activation of mGlu3 receptors enhanced GDNF production by stimulating the MAPK and the PI-3-K pathways.

In the present study, we employed various types of inhibitors to establish that activation of the FZD/LRP receptor complex is required for the augmentation of TCF/β-catenin transcriptional activity observed in MMTV-CUX1 mammary tumor cells.

In total, by using several distinct and powerful analyses we establish that activation of a β-catenin-independent pathway by Wnt7a stimulates the expression of hsa-miR29b, but not hsa-miR29a or hsa-miR29c, in NSCLC cells.