Exact(4)
This constitutes an extension of the established targeting approach that assumes process conditions to be fixed.
Along the Tete traffic corridor in Mozambique, linking Malawi and Zimbabwe, a night clinic opening between 4 and 10 PM was established targeting female sex workers (FSW) and long-distance truck drivers (LDD).
To exclude the possibility of off-target effects, three independent UAS -dNF-YAIR strains were previously established, targeting between aa63 and aa228 (UAS -dNF-YAIR63-228) (Tablet1) (Yoshiokalet al., 2008).
The time course of enzyme relocalization, in our experiments triggered at some point during oleate loading or after adding back COPI by cell cell fusion, suggests that, once LD-to-ER bridges are established, targeting is limited by diffusion across the bridges.
Similar(56)
Patients who are given the more established "targeted therapies", the best known of which is Herceptin, are already tested to ensure they are among the group in the population whose tumour has a particular genetic variation.
Established targeted insertion with right direction was confirmed at the genomic level with PCR (Fig. 1D).
Established targeted insertions were confirmed at the genomic level with PCR for all six lncRNAs as described above (Fig. S3B).
(E) RT-PCR analysis of lncRNA tagging with 4× MS2 tags using total RNA of 293T cells with established targeted insertion.
Established targeted insertion and lncRNA tagging were confirmed at the genomic level and mRNA level with PCR/RT-PCR, respectively (Fig. 1B).
Established targeted insertions were examined and confirmed at the genomic level with PCR for all six lncRNAs similarly as described above (Fig. S4B).
Chimeras were created with these homologous recombinant ES cells to establish targeted transgenic animals.
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