Sentence examples for established strictures from inspiring English sources

In daily clinical practice, most CD patients present with established strictures, representing the end-stage of the fibrotic process, and most clinicians see this scenario as an inevitable progression to a likely surgical intervention.

The inflammatory process of CD usually affects the mesenteric border of the bowel loops, so when fibrosis is established, stricturing and shortening of the mesenteric side result in compensatory dilatation of the anti-mesenteric wall.

Therefore, the current therapy of established fibrotic strictures comprises mainly endoscopic dilation as well as surgical approaches.

"Once Manders establishes the strictures that everyone else is living under, he steps back, and the heart of the play is the relationship between a mother and child".

A final diagnosis of malignancy was eventually made in 44/60 patients with indeterminate strictures established by brush cytology (n=9), endoscopic ultrasound-fine-needle aspiration (EUS-FNA) (n=1), intraductal biopsy (n=7), percutaneous biopsy (n=16), resection specimens (n=3) or clinical course (n=8).

Future clinical studies are a prerequisite to evaluate the optimal timing for anti-fibrotic treatment approaches, to elucidate the best routes of application, and to evaluate the potential of drug candidates to reach the ultimate goal: the prevention or reversal of established fibrosis and strictures in CD patients.

The sensitivity and specificity of the Mcm5 test at the 1000-cell cut point in strictures with established diagnoses were 62 and 92%, respectively.

Bile aspirates were acquired from 102 patients with biliary strictures of established (n=42) or indeterminate aetiology (n=60) and the final diagnoses are shown in Table 2.

In 30 tissue specimens from patients with malignant/benign biliary strictures, we studied Mcm2 and -5 expression by immunohistochemistry. Bile samples were also collected prospectively at endoscopic retrograde cholangiopancreatography from 102 consecutive patients with biliary strictures of established (n=42) or indeterminate aetiology (n=60).

High success rates for stone clearance and stricture dilatation were established in the present series and compare favourably with transhepatic intervention, reporting successful dilatation rates from 67to90%0% [4].

Between 2004 and 2006, 113 consecutive patients were invited to participate in the study for evaluation of indeterminate, or established, benign and malignant biliary tract strictures.