The great European news centres began to develop during the 17th century, especially in cities that were establishing sophisticated financial exchanges, such as Antwerp, Frankfurt, Amsterdam, London, and Lyons.
In addition, new computer technology (or the new availability of it) permitted independent evangelists to establish sophisticated "feedback loops" through telephone banks and direct-mail services with "personalized" letters and solicitations.
The nations that succeed in the changing and complicated business environment of the 21st century are going to be those with governments capable of establishing sophisticated "win-win" relationships with businesses at home and abroad.
Exogenous NPCs lacking the expression of major neural antigens were reliably (and for long-term) found at the level of draining lymph nodes, while establishing sophisticated anatomical interactions with lymph node cells.
The human immunodeficiency virus type I (HIV-1) encodes three structural (gag, pol and env), four accessory (vif, vpr, vpu and nef) and two regulatory (tat and rev) genes, the products of which are responsible for establishing sophisticated interactions between the virus and human host.
"The Atlantic Seaboard is a recession resistant, established and sophisticated region," she said, with a "sound commercial infrastructure.
"The industrial meat system has a very well established and sophisticated distribution network," Mr. Hunt noted, which makes its products more accessible and cheaper than the sustainable variety.
One senior European intelligence official said there was evidence that Abu Musab al-Zarqawi, the Jordanian-born militant believed to be operating in Falluja, has established a sophisticated network that has helped recruit nearly 1,000 young men from the Middle East and Europe.
Some plants, like legumes, are particularly active recruiters of friends, as they have established very sophisticated and beneficial interactions with nitrogen-fixing bacteria, also via the SYM pathway.
