In contrast, their association with renal function decline in a general population without established renal disease has not been extensively studied.
At this point, it has not been established if renal function returns to its best possible baseline immediately after the AKI trigger has stopped, or if it exists a period of time in which dysfunctional, but yet viable nephrons remains dysfunctional, thus being possible to create a concept such as "stunned nephrons" the same way stunned myocardium represents a well-recognized entity [20].
Moreover, the dynamic equilibrium concentration gradient is established by renal function and disappears, i.e. α → 1, only when renal function approaches zero [ 13].
However, it is only when a GV is found using a CL relative-error minimizing technique that GV (1) accurately predicts the late-time concentration and (2) consistently forms a model with a dynamic concentration gradient established by renal function.
Instead of selecting a younger donor to optimize graft function for the recipient, an alternative strategy, when the anticipated graft survival is acceptable, may be to select the older donor with established stable renal function whose lifetime incidence of developing ESRD would be less than the younger donor [ 21 ▪, 22].
It is already established that renal function, TnT as well as age can provide independent prognostic information, but our study focuses on how these markers can be dichotomised and combined into a simple prognostic scoring algorithm that is memoriseable and easily applied by busy clinicians.
It has been clearly established that residual renal function is related to all-cause mortality and risk of cardiovascular death in PD patients [ 28].
Having proven that etanercept could reduce relevant inflammatory signaling in the kidneys of pck rats, we next studied whether the drug could improve established markers of renal function and PKD pathology.
It is therefore hard to establish whether impaired renal function is the 'egg' or the 'chicken'.
Objectives: Cystatin C and β2-microglobulin are established serum markers of renal function in children and adults.
