Sentence examples for established rationale for from inspiring English sources
In the setting of immediate threat to life where other treatments are not proving effective, it is reasonable to use an agent when there is an established rationale for use and 'all or nothing' cases such as those described above have been reported.
In the companion paper, we established a rationale for exploring the general principles of dendritic processing using a class of Boolean functions the Multi-Cube Units (MCUs).
His embrace of racial diversity as a valid goal in university admissions, expressed in a solitary opinion in the 1978 Bakke case to which no other justice subscribed, not only established a rationale for affirmative action but frames the current debate a generation later.
These properties established a rationale for anticytokine therapeutics and their evaluation in an extensive series of clinical trials [ 28].
These observations established the rationale for the schedule-dependency and likely antitumor activity, and formed the basis for the design of the first Phase I dose escalation study.
A further limitation is that the underlying biology of suicide and attempted suicide is poorly understood so there is no established pharmacological rationale for the relations we have identified; rather, these are statistical associations worthy of further investigation to understand any underlying biological mechanisms.
The objectives of this study was to establish a rationale for repairing large anterior skull base defects with an extended pericranial flap and split calvarial bone graft; to define large anterior skull base defects as those spanning the anterior cranial measuring at least 3.0 × 4.0 cm; and to describe the surgical technique and compare it with alternative strategies.
The first derivative spectra presented in Figure 1B demonstrate the within and between substrate spectral reproducibility to establish the rationale for the SERS-based detection platform.
These results also provide insight into TRiC protein substrates and establish a rationale for the development of small-molecule inhibitors of TRiC as potential antiviral therapeutics.
The report establishes the rationale for such an operation, familiar to readers of this blog (where the "Guam option" was first proposed over a year ago).
