Sentence examples for established potential for from inspiring English sources

Mutants affecting the nucleotide pool, oxidative stress response, or mitochondrial function make up the only nonnuclear functional groups, consistent with the established potential for these pathways to influence nuclear genome integrity indirectly through their effects on oxidative base damage and Fe-S cluster formation (Huang et al. 2003; Veatch et al. 2009).

We demonstrate here that HSV-1 triggers amyloidogenic cleavages of the APP that are mediated in part by the action of β-secretase, γ-secretase, and caspase-3-like enzymes, and that result in the formation and intracellular accumulation of different APP fragments with established potential for neurotoxicity.

Forty syndromic genomic regions were selected from the DECIPHER database (http://decipher.sanger.ac.uk/) [ 43] and represented patients with neurodevelopmental delay associated with CNV findings of established potential for pathogenicity.

For example, the established potential for miR-10b to target both CDKN1A and CDKN2A mRNAs could in principle result in a p53-directed attenuation circuit of cell cycle arrest and senescence [ 62].

Given the established potential for ART to prevent HIV transmission and the failure of current interventions to produce significant reductions in HIV incidence, Granich et al sought to model the impact a test-and-treat strategy would have on the HIV epidemic.

In a thought-powered world, however, planning and execution are merely the table stakes that establish potential for leadership.

HIV integrase enzyme is well established potential target for antiretroviral therapy since a decade.

Additionally, feedback reflecting TBAs wanting to learn more and possibly even deliver care is promising in that once safety and feasibility of community-based care can be established, potential exists for training lower cadres in the provision of treatment.

However, several studies have established potential dependence of spike occurrences for different neurons.

Moreover, the enormous number of targets (many thousands) obtained suggests a vast heterogeneity among PC patients, thus requiring a large patient cohort for chip-based analyses to validate, optimize, and establish potential targets for ultimate clinical application.

"We are establishing potential judoka for Rio in 2016 and I'm very happy with the junior competitors".