Sentence examples for established obesity from inspiring English sources

64 Short-term effects of fumagillin on established obesity were evaluated in 20-week-old obese C57BL/6J mice at a dose of 1 mg/kg/day over 4 days.

In Australia, 60% of adults are overweight or obese, and many other countries show similar prevalence. 1 2 Treating established obesity and related diseases has proved challenging and costly, and requires a skilled workforce, intensive ongoing education, and counselling.

GUDCA was further identified as an intestinal FXR antagonist that improved various metabolic endpoints in mice with established obesity.

"The evidence is well established: obesity, together with the excessive consumption of fat and salt, is linked to the rising global incidence of non-communicable diseases, including some cancers, diabetes, heart disease and stroke," says the report.

That's especially important because only a very small minority — fewer than 1% by a recent estimate — of those with established obesity succeed in losing and keep off enough weight to return to a normal healthy weight.

Future studies should be designed to determine whether inhibition of myostatin signaling can help to reverse established obesity, hepatic steatosis and glucose intolerance.

A second reason for cross-ancestry comparison relates to the fine-mapping of established obesity-susceptibility loci.

FTO is an established obesity-susceptibility gene, and several loci in this gene have been reported to be associated with cancer risk.

The research is not intended to establish obesity as a risk factor for periodontal disease.

The process of adipogenesis is regulated by an elaborate network of transcription factors that coordinate the expression of hundreds of proteins responsible for establishing obesity.

One group of mice (n = 6) was fed an HF diet for 3 months before MLI to establish obesity before initiation of OA.