Sentence examples for established loci for from inspiring English sources

Schools are established loci for health promotion.

We tested 50 established loci for type 2 diabetes and related traits (fasting glucose, fasting insulin, 2 h glucose).

Several studies have been successful in identifying new CD risk variants by testing previously established loci for other immune-related diseases [ 17, 18].

Application of these expanded reference group analyses resulted in more significant evidence of association at the most compelling loci identified in the primary analysis, as well as for established loci for T1D, T2D, and CD.

More recently, investigation of interaction effects between pairs of SNPs within established loci for psoriasis identified the first G × G interactions with "compelling" evidence of association through GWA studies [The Genetic Analysis Of Psoriasis Consortium and The Wellcome Trust Case Control Consortium 2, 2010].

For example, the 180 reported loci for human height in the general population together explain no more than 10% of the genetic variance of the trait [ 3], whilst the joint effects of lead SNPs at 63 established loci for type 2 diabetes account for less than 6% of the familial aggregation of the disease [ 4].

We computed a genetic risk score based on 26 established loci for refractive error, calculated mean refractive error as a function of genetic risk score for levels of education, estimated risk of myopia in combined strata of genetic risk and educational level, and examined biological interaction according to the synergy index developed by Rothman [ 20].

Overall, GWASs have proved to be rather disappointing for identifying genetic determinants of complex traits, that is, longevity or many age-associated diseases, and established loci account only for a small proportion of trait heritability.