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This may reflect adaptations favoring the survival of organisms in non-liquid physiologic environments, which may explain in part the difficulty in eradicating some infections once they become established in solid tissues.
By simulation using a model established in solid tumors, the typical values for area under the concentration time curve are 4.03 and 22.4 µg/ml × h after a single dose of 80 and 240 mg/m given by 1-h infusion, 3.21 and 19.3 µg/ml × h by 3-h infusion, and 2.33 and 9.54 µg/ml × h by 24-h infusion, suggesting a more than dose-proportional increase of exposure.
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The distribution of Fagus sylvatica is reproduced in grey from EUFORGEN http://www.euforgen.org/distribution-maps/. Plotted symbols represent trials established in 1995 (green solid circles) and 1998 (blue solid circles) and the respective provenances tested in series from 1995 (green empty circles) and 1998 (blue empty circles).
The existence of divalent einsteinium is firmly established, especially in solid phase; such +2 state is not observed in many other actinides, including protactinium, uranium, neptunium, plutonium, curium and berkelium.
We have established in our laboratory a solid tumor model with nude mice bearing ANDO-2 human melanoma cell line.
Such an approach has been achieved with the response evaluation criteria in solid tumors (RECIST) criteria for solid tumors established in 2000.
The role of CSCs was initially established in leukaemia, and more recently in solid tumours including melanomas [ 14, 15], glioblastomas [ 16], and epithelial cancers [ 17- 21].
An approximate topological optimization model for suppressing 'localized modes' of vibrating Cauchy solids is established in this paper.
It would be heartening to see a solid working democracy established in Afghanistan.
In a third approach, we used solid 518A2 tumors established in C.B.17 SCID/SCID mice [13] to detect HMW-MAA-reactive rabbit Abs by IHC.
To determine whether honokiol could suppress tumor growth in vivo, solid tumors were established in mice and the anti-tumor effect of repeatedly injected honokiol was studied.
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