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Neuronal circuitries established in development must persist throughout life.
When and how epigenetic patterns are established in development is a focus of current research.
The evident hierarchy of specific binding, nonspecific binding, partial chromatin binding, failure to bind mitotic chromosomes, and mitotic instability reflects the factors' developmental roles in gene activation, and suggest that re-activation of the genome following mitosis involves a replay of the network by which the cell type was established in development.
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Neither the right to health nor the right to development has been established in the development of health system or in providing health care.
Although the crosstalk between BMP and TGFβ signaling pathways is well established in bone development, the relationship between these two pathways is less well defined during cartilage development and postnatal homeostasis.
Additionally, although face validity was established in the development of the questionnaire, it is possible that some of the participants did not understand the quality descriptors or the triggers but answered the question regardless, which would skew the data.
Specific roles of Pax6 were established in the development of both tissues [7], [34].
The role of SHP-2 in RAS/ERK signaling (Fig. 2) is thus well established in tumor development.
Gathering all of the formulations above, we catch a sight of many milestones established in the development of neurogenesis as well as obstacles being unfathomed.
Epigenetic aberrations, including DNA methylation and histone modifications, are well established in the development and progression of ovarian cancer (Barton et al, 2008; Balch et al, 2009).
This supports the hypothesis that the relative expression patterns of grain yield associated genes have already been established in early development stages [ 11].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com