Sentence examples for established in cell from inspiring English sources

Notably, their therapeutic efficacy was clearly dependent upon the level of internal hypoxia established in cell aggregates.

Because it has been established in cell culture that methylation of the rRNA promoter regulates the transcription of rRNA [31] [34], rRNA expression in suicide subjects and controls was investigated.

Although well established in cell lines and today frequently used in transgenic mouse strains, certain limitations apply to these systems, mainly insufficient tightness of gene-repression and/or moderate induction levels, e.g., due to ineffective delivery and targeting of agonists to the cell type/tissue of interest, as well as stochastic epigenetic transgene silencing [4] [5].

This was possible because the AA signature has been established in cell culture [ 14, 25] and because previous epidemiological data have linked AA to UTUCs [ 24, 28, 51].

GPCR mRNA and protein turnover has been primarily established in cell lines expressing native or cloned GPCRs and could be quite different in the PVN/SON microenvironment.

Roles for butyrate have been established in cell differentiation, proliferation, motility and in particular induction of cell cycle arrest and apoptosis [ 5- 7].

We first lay out the rationale for designing CompEL as a method that models the driving force for ion permeation through channels the way it is established in cells, i.e., by electrochemical ion gradients across the membrane.

The Ctr4 Ctr5 association was selected as a proof-of-concept model, since this interaction has previously been established in cells grown under conditions of copper starvation [21], [22].

Such experimental methodologies therefore result in latency being established in cells that may otherwise have supported lytic cycle replication.

In later life, reactivation of latent VZV established in cells of the dorsal root ganglia after primary infection, may cause herpes zoster (shingles).

This strategy allowed us to find UBXN2A partners within two different protein protein interaction networks established in cells with and without genotoxic stress.