Sentence examples for established in absence from inspiring English sources

This fact, together with their isolation in pure culture from internal organs might suggest a clinical significance; however the role of C. shigense as the causative agent of the disease episodes in trout cannot be undoubtedly established in absence of experimental infections trials.

Further studies suggested that these chromatin marks are only established during the maternal-zygotic transition and could be established in the absence of specific transcriptional regulators.

Whilst ASCE/SEI 43-05 providenoughugh flexibility for the selection of other user-specified quantitative performance goals, there is no guidance on how quantitative performance goals should be established in the absence of extensive operational experience accompanied by data derived from rigorous SPRA applications.

AML 2003-114, whereby long-term cultures could be established in the absence of cytokines, also contained constitutively activated STAT5.

Maternal inheritance of TSE, responsible for its epigenetic behavior, can thus be established in the absence of the target transgene.

Remarkably, we show in this study, that vole TS-like cells can be established in the absence of FGF4 and heparin.

Our bisulfite results support the conclusion that G9a is essential for full methylation of the promoter, in agreement with previously published bisulfite data on the promoter of the gene [10], but it is clear that de novo methylation elsewhere within the 2 kb regulatory region can be established in the absence of G9a.

It was initially thought that this lack of hybridization reflected the global transcriptional repression of X-linked genes but recent work suggests that the Cot-1 hole represents a repressive nuclear compartment that can be established in the absence of genic silencing [2], [3].

It is noteworthy that all these criteria are established in the absence of laxative use.

Our simulations demonstrated that genetic clines could be established in the absence of divergent selection.

However, its safety and efficacy are not well established, in the absence of randomized trials [ 16].