The phrase "established importance" is correct and usable in written English.
It can be used when discussing the significance or value that has been recognized or acknowledged over time.
Example: "The established importance of biodiversity in maintaining ecosystem health cannot be overstated."
Alternatives: "recognized significance" or "acknowledged value."
Relative size established importance: the ruler dwarfed the generally high official, while the tomb owner dwarfed his wife and, still more so, his children.
Besides their established importance in the NMD process per se, NMD components have also been reported to play roles in other cellular pathways.
Replication of our association findings in the FHS cohort and the gene's established importance in both chondrogenesis/cartilage formation and obesity-related insulin resistance further suggests the gene's pleiotropic roles in both obesity and osteoporosis.
Based on the well established importance of fungal laccases and related enzymes in lignin degradation [ 48, 49], phenoloxidases/laccases are also relevant to industrial lignocellulose pretreatment.
We discuss predicted functions for the gene products of MLH1, PMS2 and EPHB4, all of which have an established importance for colorectal cancer [ 67, 68].
In this study, we included all breast cancer cases diagnosed within a population of over 3.6 million, and estimated the relative risk of death in relation to surgical workload after adjusting for a range of patient factors of established importance.
Second, LMICs with substantial pharmaceutical markets, such as India, Brazil and Thailand, can provide leadership and establish importance precedence by asserting the flexibilities available under TRIPS to protect public health.
Random Forests bias-corrected selection frequency, a novel importance measure, performed better in these tasks than the established permutation importance and RSS importance.
Having established the importance of residues in position 5 and 6, we then wanted to explore the importance of Lys in position 2 in substrate specificity.
Published in France as a cheap edition, it immediately established his importance.
America's main fishery law established the importance of scientific quotas in 1976.
