Over the past decade, electrospraying has proven to be a promising method for the preparation of amorphous solid dispersions, an established formulation strategy to improve the oral bioavailability of poorly soluble drug compounds.
Multi-fluid interfaces are represented using field variables (interface functions) with associated transport equations that are augmented, with respect to an established formulation, to enforce a selected interface thickness.
Delivery devices using liquid vaccine formulations are advantageous, as established vaccine formulations can be used as provided without the need for reformulation.
The performance of the proposed formulation is assessed with reference to well-documented physical tests and established analytical formulations.
Two established whitecapping formulations in SWAN are investigated: one dependent on mean spectral wave steepness, and the other on local spectral steepness.
The new equations are likely to find widespread application in many types of flood inundation modelling and should provide a useful additional tool, alongside more established model formulations, for a variety of flood risk management studies.
This paper derives local formulae to estimate bed roughness and suspended transport and present a method to calculate net sediment transport at tidal inlet systems, combining field data and a range of well established empirical formulations.
These vesicles exhibit superior killing efficacy of cancer cells compared to established liposome formulations, and their killing efficacy is similar to the effect of combined free doxorubicin and free antiHER2/neu antibody.
A proper IVIVC model should be established using formulations with different release rates.
In addition, their antibacterial modes of action need to be established and formulations for improving antibacterial potency and stability need to be developed.
At present, in the absence of head-to-head trials against established oral formulations, the main advantage of this product seems to be convenience-related [ 49- 51].
