Sentence examples for established for prolonged from inspiring English sources

Hence we propose that once the tumour has been established for prolonged periods of time, multiple layers of immune tolerance may prevent the efficacy of antitumour responses.

The potential of adenovirus based vectors to infect the liver cells after intravenous injection makes them suitable vectors for establishing a prolonged systemic delivery of the encoded protein.

A delay in disease progression was seen, suggesting that this population has at least transient regulatory properties and that other Tregs or other IL-10-producing cells are necessary for establishing prolonged tolerance.

In general, stable contacts with beta cells were rare, as for instance only 1 cell was found to establish prolonged interaction in movie S3C.

- Renal replacement therapy (RRT) has been established for more than 50 y, and the main focus is to prolong a high quality of life with a low rate of comorbidities.

Fixed dates were established for trials.

Area boundaries are arbitrary, established for convenience.

To investigate these mechanisms further, and to enable use of bryostatin for prolonged periods, the effect of a vasodilator on the established effects of bryostatin on calf metabolism was studied using 31P magnetic resonance spectroscopy and near infrared spectroscopy.

The effect of these small-molecule inhibitors on established cancer cell lines, whose mesenchymal properties emerged during tumorigenesis and were maintained for prolonged periods of time in culture, was more modest but nonetheless remarkable.

This research has established that the biological process of an MEC will to work at low temperatures with real wastewater for prolonged periods.

Shackling for prolonged periods.