Angry over the rising cost of scientific, technical and medical journals, a group of university libraries is starting a campaign to persuade researchers to consider abandoning their established journals for less expensive upstarts.
Thus, although it is increasingly apparent that the class I HDAC enzymes are clinically relevant for cancer, this is less established for the class II enzymes.
Prognosis is related primarily to stage, with nuclear grading less established for this subtype [19].
This review focuses on C C bond formation by enzymes, which are less established for biocatalysis, which have gained increased significance recently or which have been reported for the first time.
On the other hand, there are comparatively less methods established for the advanced differential equations.
Indeed, CD28 B7 interactions are important for the activation of naive T cells, but this is less well established for the activation of memory CD4+ T cells [ 10].
Moreover, because this population is frequently under-represented in clinical trials the effectiveness and toxicity profile of standard treatment protocols are less well established for the elderly [ 4].
Reference values are less well established for alternative markers, making the clinical relevance of changes in other markers harder to interpret.
In contrast to NOX signaling, (or, more likely, as is less well established for NOX signaling) the proximity of protein targets of NO to the RNS source is frequently imparted by direct interaction with NOS.
However, the Institute considered that the cost-effectiveness of insulin glargine was less well established for people with type 2 diabetes, principally because of the lower frequency of hypoglycaemic episodes among this group and consequently the relatively limited scope for improvement.
