Sentence examples for established end from inspiring English sources

Patients' self-assessment of HRQOL is now an established end point for treatment comparisons in many cancer disease sites (Bottomley et al, 2003), particularly in advanced disease (Efficace et al, 2004a; Bottomley et al, 2005).

As part of a comprehensive evaluation of lesser declines in eGFR as alternative end points, we describe the consistency of treatment effects of intervention on the alternative and established end points in past trials.

The currently established end points for clinical trials of progression of chronic kidney disease (CKD) are end-stage renal disease and doubling of serum creatinine level, which approximates a 57% decline in estimated glomerular filtration rate (eGFR).

It is suggested that when proof-of-concept is based on newly established end points, a greater understanding of the correlation to the mechanism of action and putative links to clinical benefit must be considered.

There is interest in surrogate end points for clinical trials of chronic kidney disease progression because currently established end points—end-stage renal disease (ESRD) and doubling of serum creatinine level are late events, requiring large clinical trials with long follow-up.

The currently established end points of end-stage renal disease and doubling of serum creatinine level, equivalent to a 57% decline in estimated glomerular filtration rate (eGFR), are late events in chronic kidney disease (CKD), requiring large clinical trials with long follow-up.

Established 1964.

Established: 1984.

Established 1980.

Bristol Community College was established (1966) in Fall River.

The Great Meadows National Wildlife Refuge (established 1944) is nearby.