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A visual prosthesis has the significant advantage that restoration of function could be achieved by stimulation of nerve fibers that had been properly established during development.
Organism viability relies on the stable maintenance of specific chromatin landscapes, established during development, that shape cell functions and identities by driving distinct gene expression programs.
To investigate when spatial genome organization is first established during development, we examined chromatin conformation during Drosophila embryogenesis and observed the emergence of chromatin architecture within a tight time window that coincides with the onset of transcription activation in the zygote.
In order to determine the period at which this non-random CT order is established during development, we performed fluorescence in situ hybridization, on three-dimensionally preserved bovine preimplantation embryos generated by in vitro fertilization and investigated the distribution of BTA 19 and 20 CTs.
How might the dispersed chromatin state be established during development?
Cognitive abilities are rapidly established during development, stabilize in adults and may decline with aging.
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Dormancy is established during seed development on the parental plant [ 35]; therefore, this trait is likely programmed during seed development.
Patterns of DNA methylation are established during embryonic development and faithfully copied through somatic cell divisions.
How this diversity of MbDNs is established during brain development is only starting to be unraveled.
Face validity, with both non-concussed (n = 7) and concussed athletes (n = 10), was established during the development of the symptom questionnaire.
How these populations are established during the development of the conducting airways and distal lungs may provide insight into their regulation in adult tissues.
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