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Although safe zones for screw fixation in both normal and dysmorphic second sacral segments have been established, challenges exist in achieving proper fixation into the S2 body because of its smaller size and decreased tolerance of variant screw trajectories [3, 11, 12].
These were considered appropriate based on the severity of presenting symptoms and established challenges of case identification and health seeking behaviour for the latter conditions.
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The determination of an objective versus a subjective binge is an established challenge in the evaluation of eating disorders.
While under-reporting is a well established challenge of passive surveillance systems, the problems associated with NHP ADR monitoring are more complex than those associated with pharmaceutical drugs.
I used my savings from my former salary and the income from my business to finance my dreams and establish Challenging Heights, which I did unofficially in 2003, and then registered in 2005.
Instead of starting with spatial issues, the first step of the project established the challenges for urban development on functional grounds.
Social dominance within the choruses is established through challenges, threats, and other physical displays.
Once the position is established, the challenge becomes finding a good set of rules.
This presumption was so strong that formalized I.C. mechanisms established to challenge assumptions and groupthink were not utilized.
But it's good to see established professors challenged to acknowledge contingent workers, who now comprise the preponderance of the faculty community.
The fact that this manifesto was made at St Anne's, a college established to challenge women's historical exclusion from Oxbridge, adds irony to insult.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com